script for kinetic fitting of β-lactam hydrolysis using the lambert function Search Results


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Novozymes limited calb-catalyzed ring-opening polymerization of β-lactam
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Structures of <t>siderophore-β-lactam</t> Trojan Horse antibiotics. These monocatecholate and hydroxypyridinone siderophore–antibiotic conjugates target ferric catecholate uptake pathways in Gram (−) cells. The iron chelation moieties are colored blue. Cefiderocol (FDC) contains a monocatecholate siderophore moiety and is the only FDA-approved siderophore-conjugated antibacterial drug.
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IDEXX β-lactam test kit
Structures of <t>siderophore-β-lactam</t> Trojan Horse antibiotics. These monocatecholate and hydroxypyridinone siderophore–antibiotic conjugates target ferric catecholate uptake pathways in Gram (−) cells. The iron chelation moieties are colored blue. Cefiderocol (FDC) contains a monocatecholate siderophore moiety and is the only FDA-approved siderophore-conjugated antibacterial drug.
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Structures of <t>siderophore-β-lactam</t> Trojan Horse antibiotics. These monocatecholate and hydroxypyridinone siderophore–antibiotic conjugates target ferric catecholate uptake pathways in Gram (−) cells. The iron chelation moieties are colored blue. Cefiderocol (FDC) contains a monocatecholate siderophore moiety and is the only FDA-approved siderophore-conjugated antibacterial drug.
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Structures of <t>siderophore-β-lactam</t> Trojan Horse antibiotics. These monocatecholate and hydroxypyridinone siderophore–antibiotic conjugates target ferric catecholate uptake pathways in Gram (−) cells. The iron chelation moieties are colored blue. Cefiderocol (FDC) contains a monocatecholate siderophore moiety and is the only FDA-approved siderophore-conjugated antibacterial drug.
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Structures of <t>siderophore-β-lactam</t> Trojan Horse antibiotics. These monocatecholate and hydroxypyridinone siderophore–antibiotic conjugates target ferric catecholate uptake pathways in Gram (−) cells. The iron chelation moieties are colored blue. Cefiderocol (FDC) contains a monocatecholate siderophore moiety and is the only FDA-approved siderophore-conjugated antibacterial drug.
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Meridian HealthComms β-lactam combinations
Structures of <t>siderophore-β-lactam</t> Trojan Horse antibiotics. These monocatecholate and hydroxypyridinone siderophore–antibiotic conjugates target ferric catecholate uptake pathways in Gram (−) cells. The iron chelation moieties are colored blue. Cefiderocol (FDC) contains a monocatecholate siderophore moiety and is the only FDA-approved siderophore-conjugated antibacterial drug.
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IDEXX snap β-lactam test kit
Structures of <t>siderophore-β-lactam</t> Trojan Horse antibiotics. These monocatecholate and hydroxypyridinone siderophore–antibiotic conjugates target ferric catecholate uptake pathways in Gram (−) cells. The iron chelation moieties are colored blue. Cefiderocol (FDC) contains a monocatecholate siderophore moiety and is the only FDA-approved siderophore-conjugated antibacterial drug.
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Molecular Networks GmbH corina program
Structures of <t>siderophore-β-lactam</t> Trojan Horse antibiotics. These monocatecholate and hydroxypyridinone siderophore–antibiotic conjugates target ferric catecholate uptake pathways in Gram (−) cells. The iron chelation moieties are colored blue. Cefiderocol (FDC) contains a monocatecholate siderophore moiety and is the only FDA-approved siderophore-conjugated antibacterial drug.
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Structures of siderophore-β-lactam Trojan Horse antibiotics. These monocatecholate and hydroxypyridinone siderophore–antibiotic conjugates target ferric catecholate uptake pathways in Gram (−) cells. The iron chelation moieties are colored blue. Cefiderocol (FDC) contains a monocatecholate siderophore moiety and is the only FDA-approved siderophore-conjugated antibacterial drug.

Journal: Chemical reviews

Article Title: Iron Acquisition Systems of Gram-negative Bacterial Pathogens Define TonB-Dependent Pathways to Novel Antibiotics

doi: 10.1021/acs.chemrev.0c01005

Figure Lengend Snippet: Structures of siderophore-β-lactam Trojan Horse antibiotics. These monocatecholate and hydroxypyridinone siderophore–antibiotic conjugates target ferric catecholate uptake pathways in Gram (−) cells. The iron chelation moieties are colored blue. Cefiderocol (FDC) contains a monocatecholate siderophore moiety and is the only FDA-approved siderophore-conjugated antibacterial drug.

Article Snippet: His work at Venatorx supports the clinical-stage cefepime–taniborbactam combination and novel non- β -lactam inhibitors of penicillin-binding proteins.

Techniques: